Kaurenoic acid

CAS No. 6730-83-2

Kaurenoic acid ( CCRIS 1514; Kauren-19-oic acid )

Catalog No. M18978 CAS No. 6730-83-2

Kaurenoic acid has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 53 In Stock
10MG 87 In Stock
25MG 158 In Stock
50MG 236 In Stock
100MG 350 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Kaurenoic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Kaurenoic acid has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level.
  • Description
    Kaurenoic acid has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level. Kaurenoic acid exerts a uterine relaxant effect acting principally through calcium blockade and in part, by the opening of ATP-sensitive potassium channels. Kaurenoic acid exhibits an analgesic effect in a consistent manner and that its mechanisms involve the inhibition of cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway. Kaurenoic acid derivatives have an antimicrobial activity of substituted on carbon-15 at concentrations greater than or equal to 250 μg/ml. Kaurenoic acid has inhibitory effects on the LPS-induced inflammatory response in RAW264.7 macrophages.
  • Synonyms
    CCRIS 1514; Kauren-19-oic acid
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    6730-83-2
  • Formula Weight
    302.45
  • Molecular Formula
    C20H30O2
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    C[C@@]12CCC[C@@]([C@H]1CC[C@]34[C@H]2CC[C@H](C3)C(=C)C4)(C)C(=O)O
  • Chemical Name
    (4R,4aS,6aS,9S,11aR,11bS)-4,11b-dimethyl-8-methylenetetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Okoye T C, et al. Anticonvulsant effect of kaurenoic acid isolated from the root bark of Annona senegalensis.[J]. Pharmacology Biochemistry & Behavior, 2013, 109(8):38-43.
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